CPT® 2024 Updates: New Codes, Revisions, and Effective Dates


Curious about the upcoming procedure codes for the new year? Your curiosity ends here!

The CPT® 2024 update will incorporate 153 fresh codes dispersed throughout the code book. These additions encompass various sections such as Evaluation and Management, several Surgery subsections (including Musculoskeletal System, Respiratory System, Cardiovascular System, Urinary System, Female Genital System, and Nervous System), as well as the Radiology section, and Pathology and Laboratory.

This expansion encompasses the recently introduced COVID-19 codes, which became effective on September 11, 2023, for Medicare. Additionally, there are 73 codes that have undergone revisions, including some E/M code updates. Moreover, 102 codes have been removed, primarily from the categories of pathology and laboratory codes, along with Category III new technology codes.

In total, the annual update has brought about 349 editorial alterations, as reported by the American Medical Association (AMA).

Effective Dates Vary

The majority of the code modifications in this annual update of CPT® will take effect on January 1, 2024, with a few exceptions. For instance, the new code 0019M pertaining to Cardiovascular disease, which involves the analysis of protein biomarkers using aptamer-based microarray and algorithm to estimate the 4-year likelihood of a coronary event in high-risk populations, will be effective from October 1, 2023.

Similarly, the new codes encompassing multianalyte assays with algorithmic analyses and proprietary laboratory analyses, denoted as 0402U-0419U, will also come into effect on October 1, 2023.

In the case of the new codes associated with respiratory syncytial virus (RSV), specifically 90380-90381, they were unveiled in July 2023 and were immediately activated on July 17, 2023.]

The descriptors for the following codes are revised, effective Oct. 1, 2023. (Changes are in bold.)

 CPT Code 0269U Hematology (autosomal dominant congenital thrombocytopenia), genomic sequence analysis of 22 genes, blood, buccal swab, or amniotic fluid
 CPT Code 0271U Hematology (congenital neutropenia), genomic sequence analysis of 24 genes, blood, buccal swab, or amniotic fluid
 CPT Code 0272U


Hematology (genetic bleeding disorders), genomic sequence analysis of 60 genes and duplication/deletion of PLAU, blood, buccal swab, or amniotic fluid, comprehensive
 CPT Code 0274U


Hematology (genetic platelet disorders), genomic sequence analysis of 62 genes and duplication/deletion of PLAU, blood, buccal swab, or amniotic fluid
 CPT Code 0277U


Hematology (genetic platelet function disorder), genomic sequence analysis of 40 genes and duplication/deletion of PLAU, blood, buccal swab, or amniotic fluid
 CPT Code 0278U


Hematology (genetic thrombosis), genomic sequence analysis of 14 genes, blood, buccal swab, or amniotic fluid
 CPT Code 0362U


Oncology (papillary thyroid cancer), gene-expression profiling via targeted hybrid capture-enrichment RNA sequencing of 82 content genes and 10 housekeeping genes, fine needle aspirate or formalin-fixed paraffin-embedded (FFPE) tissue, algorithm reported as one of three molecular subtypes


Finally, in April 2023, the descriptor for CPT Code 0095U, which pertains to Eosinophilic esophagitis and involves enzyme-linked immunosorbent assays (ELISA) for Eotaxin-3 (CCL26) and major basic protein (PRG2), conducted on specimens obtained via an esophageal string test device, with the results reported as the probability of active or inactive eosinophilic esophagitis, was modified.